COMDTINST M16721.48
Medications Subject to Further Review
7-7
j. Sleep Aids (Medications to help people fall asleep):
(1) Over-the-counter (OTC) medications to help with sleep include, but are not
limited to diphenhydramine (Benadryl, Sominex, Tylenol PM, Compoz Nighttime
Sleep Aid, ZZZQuil) and doxylamine (Unisom). Mariners are cautioned against
acting under the authority of a credential while under the influence of sleep
medications that can cause drowsiness or impairment, or that carry warnings that
caution against driving or operating heavy machinery.
(2) Prescription sleep medications and non-benzodiazepine sedative hypnotic
medications. Examples include, but are not limited to zolpidem (Ambien,
Intermezzo, Zolpimist), eszopiclone (Lunesta), and zaleplon (Sonata). Due to the
risk of impaired cognitive ability, judgment, and reaction time, use of non-
benzodiazepine sedative hypnotic medications is disqualifying. The medication
and the underlying condition will be reviewed to determine whether the mariner
qualifies for a waiver under 46 CFR 10.303. Waivers for use within 12 hours
prior to, or while acting under the authority of a credential will only be approved
on a case-by-case basis if the Coast Guard determines that there are exceptional
circumstances that mitigate risk to public safety. See Paragraph I (Medication
Waivers Requiring Special Consideration) of this Chapter.
k. Legally Prescribed Controlled Substances.
Examples include, but are not limited to, opiate and opioid pain medication such as
Tylenol with codeine, oxycodone (Percocet), hydrocodone (Vicodin), hydromorphone
(Dilaudid), tramadol (Ultram), methadone, and bruprenorphine (Suboxone). Due to
the risk of impaired cognitive ability, judgment, and reaction time, use of legally
prescribed controlled substances is disqualifying. The medication and the underlying
condition will be reviewed to determine whether the mariner applicant qualifies for a
waiver under 46 CFR 10.303. Waivers for use within 12 hours prior to, or while
acting under the authority of a credential will only be approved on a case-by-case
basis if the Coast Guard determines that there are exceptional circumstances that
mitigate risk to public safety. See Paragraph I (Medication Waivers Requiring
Special Consideration) of this Chapter.
l. Medical Use of Hallucinogens.
Examples include, but are not limited to, medical marijuana (use of the marijuana
plant), nabinol, nabiximols (Sativex), tetrahydrocannabinol, dronabinol (Marinol),
Epidiolex, peyote, ecstasy, and topical marijuana or cannabinoid preparations. Even
if legalized by a state, use of these substances is disqualifying and will not be waived
under any circumstances.
m. Muscle Relaxants.
Examples include, but are not limited to carisoprodol (Soma), cyclobenzaprine
(Flexeril), and methocarbamol (Robaxin). The medication and the underlying
condition will be reviewed to determine whether the mariner applicant qualifies for a